The AMP Core Group, a smaller group of committed members, comes together twice a year to discuss and plan AMP activities and members take a leading role in all activities coordinated by AMP.
List of AMP Core Group members as of June 2025:
| Catholic Relief Services | Dominique Guinot |
| Directorate of Malaria Control. Ministry of National Health Services, Pakistan | Muhammad Mukhtar |
| Independent participant | David Gittelman |
| Independent participant | Joseph Lewinski |
| International Federation of Red Cross and Red Crescent Societies (IFRC) | Marcy Erskine
Jason Peat |
| International Public Health Advisors | Jessica Rockwood |
| Malaria Partners International | Drake Zimmerman |
| Milliner Global Associates | John Milliner |
| Path | Hannah Koenker |
| Results in Health | Cédric Mingat |
| The Global Fund to fight AIDS, Tuberculosis and Malaria | Kate Kolaczinski |
| United Nations Foundation | Patty Sanchez |
| United States Agency for International Development (USAID/PMI) | Lilia Gerberg |
| World Health Organization-Global Malaria Programme | Emmanuel Chanda |
| World Vision | Gagik Karapetyan |